Restoring Synaptic Connections in the Inner Ear after Noise Damage


Prolonged exposure to noise results in loss of ribbon synapses, composed in part by superclusters of neurotransmitter vesicles in the sensory hair cells of the cochlea. Expression of a nerve growth factor in mouse cochlea mitigates noise-induced damage and hearing loss


Source Information


From the National Institute on Deafness and Other Communication Disorders, Bethesda, MD (L.L.C.); and the Department of Otolaryngology–Head and Neck Surgery, Duke University Medical Center, Durham, NC (D.L.T.).
Read more here:  http://www.nejm.org/doi/full/10.1056/NEJMcibr1413201