Restoring Synaptic Connections in the Inner Ear after Noise Damage

Lisa L. Cunningham, Ph.D., and Debara L. Tucci, M.D. New England Journal of Med 2015; 372:181-182January 8, 2015DOI: 10.1056/NEJMcibr1413201
Prolonged exposure to noise results in loss of ribbon synapses, composed in part by superclusters of neurotransmitter vesicles in the sensory hair cells of the cochlea. Expression of a nerve growth factor in mouse cochlea mitigates noise-induced damage and hearing loss

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From the National Institute on Deafness and Other Communication Disorders, Bethesda, MD (L.L.C.); and the Department of Otolaryngology–Head and Neck Surgery, Duke University Medical Center, Durham, NC (D.L.T.). Read more here: